Volume 45 Number 4

Severe surgical wound dehiscence with secondary infection and temporary ileostomy following latrogenic bowel injury after myomectomy: challenges and management in a low-resource setting

Jeffrey Tetteh Doku, Harriet Oppong Gyamfi

Keywords ileostomy, iatrogenic bowel injury, mucocutaneous separation, stoma siting, wound dehiscence

For referencing Doku JT, Gyamfi HO. Severe surgical wound dehiscence with secondary infection and temporary ileostomy following latrogenic bowel injury after myomectomy: challenges and management in a low-resource setting. WCET® Journal 2025;45(4):40-48.

DOI 10.33235/wcet.45.4.40-48

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Author(s)

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Abstract

This case study aims to highlight an improvised and resource-conscious approach to managing severe surgical wound dehiscence complicated by secondary infection and temporary ileostomy formation following an iatrogenic bowel injury that occurred during a myomectomy. It also seeks to demonstrate how innovative wound management strategies were employed to both control and contain faecal output. These included the use of anti-motility medication (loperamide), stool-thickening foods and an Eakin fistula pouch. Together, these measures facilitated wound debridement and promoted spontaneous healing despite challenges, such as poor stoma siting and mucocutaneous separation in a low-resource setting.

Methods The principles of fistula management sepsis control, nutritional support, anatomy definition, and procedure planning (SNAP) were applied in managing this complex wound. A multidisciplinary team approach was implemented, involving surgeons, stoma care specialists, a clinical psychologist, ward nursing staff and nutritionists. Family members were actively engaged in decision-making and provided essential financial and emotional support. Additional management strategies focused on containing faecal output, promoting wound debridement, preventing infection and supporting spontaneous healing

Results The patient responded positively to the multidisciplinary plan of care within a low-resource clinical environment. Faecal output was effectively controlled and contained using an improvised fistula management technique, which minimised wound contamination and facilitated progressive debridement. Gradual development of healthy granulation tissue was observed, leading to spontaneous wound contraction and eventual closure without the need for further surgical intervention. The patient’s nutritional status and overall well-being improved significantly throughout the recovery period.

Introduction and current evidence

Surgical wound dehiscence complicated by secondary infection remains a serious postoperative complication, particularly in patients who have undergone emergency abdominal surgery with the creation of a stoma.¹,² Myomectomy is a surgical procedure performed to remove uterine fibroids while preserving the uterus. Although generally safe, it can be technically demanding due to the close proximity of the uterus to the bowel and other pelvic structures.3 During complex or emergency surgery such as myomectomy, accidental injury to the bowel, referred to as an iatrogenic bowel injury may occur. An iatrogenic bowel injury is an unintended perforation or damage to the bowel during surgery, which increases the risk of contamination, infection and subsequent wound breakdown.4-6

When such an injury occurs, the creation of a temporary stoma (such as an ileostomy) is often necessary to divert faecal output, protect the distal bowel and allow healing of the injured segment or associated anastomosis.6 However, in emergency situations, stoma siting may be suboptimal due to time constraints or limited preoperative planning, resulting in appliance leakage, skin irritation and further wound contamination.5-6 Mucocutaneous separation, defined as the partial or complete detachment of the stoma from the surrounding skin, may also occur early in the postoperative period.7 This condition exposes the underlying tissue, increasing the risk of infection, delays healing and increases patient discomfort.

Electrolyte imbalance is another potential complication, particularly in patients with high-output ileostomies, as excessive fluid and electrolyte losses can lead to dehydration and metabolic disturbances.8

In low-resource settings, such as Ghana, managing complex abdominal wounds with concurrent stoma care is particularly challenging due to the limited availability of advanced wound care materials, personnel trained in stoma and wound care and specialised equipment.9,10,11 Effective management therefore requires a multidisciplinary approach involving surgical, nursing, nutritional and psychosocial expertise, as well as active family participation in care.9-12 Adherence to wound bed preparation principles, including debridement, infection control, moisture balance, and tissue optimisation, is essential for achieving successful outcomes.13,14

Negative Pressure Wound Therapy (NPWT), a technique that applies controlled sub-atmospheric pressure to a wound to promote granulation tissue formation and remove exudate, has demonstrated effectiveness in managing surgical wound dehiscence both with and without associated stomas.15,16,17 Evidence indicates that NPWT reduces infection rates, accelerates wound closure and enhances patient comfort.18,19 However, in resource-limited environments, the lack of NPWT systems, high costs of stoma appliances and inadequate access to specialist wound care services continue to hinder optimal management.20 These challenges compel resource-conscious clinicians to improvise and contextually adapt wound management strategies and products based on established principles of fistula care (SNAP)21 and reconstructive techniques.20-22

This case study therefore describes an innovative, resource-conscious approach to managing severe surgical wound dehiscence complicated by secondary infection and temporary ileostomy following an iatrogenic bowel injury sustained during myomectomy. It emphasises the impact of poor stoma siting and mucocutaneous separation on wound healing and recovery within a low-resource clinical setting.

Personal and clinical history

The patient is a 56-year-old female with a medical history of uterine fibroids and hypertension who underwent an elective myomectomy at the Ejisu Government Hospital in the Ashanti Region of Ghana on 31 July 2019. The procedure was performed under general anesthesia, and the abdominal wound was closed primarily in layers using absorbable sutures for the fascia and subcutaneous tissue, and interrupted non-absorbable sutures for the skin.

The immediate postoperative course was initially uneventful. However, on the first postoperative day (1 August 2019), the wound dressing was noted to have turned green, prompting a return to the operating theatre for re-exploration and wound revision. Subsequently, the patient developed abdominal distension, purulent wound discharge and partial wound dehiscence. Within two days, the wound breakdown progressed, exposing the underlying bowel. An iatrogenic bowel injury with faecal contamination was identified intraoperatively, necessitating the creation of a diverting ileostomy.

On the second postoperative day following the relaparotomy (3 August 2019), the patient was referred and transferred to the Komfo Anokye Teaching Hospital (KATH), a tertiary referral center in Kumasi, for specialised surgical, wound and stoma management.

Comorbid conditions

The patient’s past medical history revealed hypertension, managed with labetalol, and a prior diagnosis of uterine fibroid. There were no additional comorbidities, such as diabetes mellitus or renal impairment.

Medications

Her pharmacological profile included labetalol for blood pressure control. She occasionally self-medicated with over-the-counter analgesics and antipyretics for mild symptoms, such as headache and fever.

Allergies

The patient reported no known allergies to food or drugs.

Social aspects

The patient was married with three children (two males and one female) and lived with her family in her privately-owned home. She maintained regular employment and an active lifestyle, beginning her day early to perform household activities before work. She had strong family and community relationships and received consistent emotional and financial support throughout her illness.
Despite her stable socioeconomic status, the patient expressed psychosocial distress, attributing her prolonged postoperative complications to spiritual causes or witchcraft (a belief that reflects cultural interpretations of illness in parts of Ghana). These perceptions influenced her emotional well-being and initial coping responses during recovery.

Wound, ostomy and continence assessment

Aetiology

The wound complication originated from an iatrogenic injury to the small bowel sustained during the myomectomy procedure. The affected bowel segment was repaired primarily without resection; however, postoperative breakdown of the repair site led to faecal leakage and secondary peritonitis, necessitating the creation of a diverting ileostomy to control sepsis and prevent further contamination of the surgical wound.

Type of stoma

An end ileostomy was constructed; however, complete mucocutaneous separation developed around the stoma site, resulting in difficulty achieving adequate adhesion of the ostomy appliance. This led to persistent faecal leakage and contamination of the wound bed, further complicating wound management.

Stoma output

The stoma produced a high output averaging approximately 2.5 litres per 24 hours, resulting in fluid and electrolyte imbalance and peristomal skin maceration due to leakage of semi-fluid chyme rich in digestive enzymes.

Stoma care

The stoma was placed in the right lower quadrant of the abdomen but was poorly sited, as it lay below the umbilical line and outside the rectus abdominis muscle and partly within an abdominal skin fold. This suboptimal positioning made it difficult to achieve a secure seal with the ostomy appliance. Consequently, early pouching attempts failed due to frequent leakage of stool and peristomal skin maceration, which further contaminated the adjacent wound and delayed wound healing. Subsequent management required creative adaptation of wound care techniques, including improvised containment of faecal output and meticulous protection of the peri wound skin.

Urinary continence

The patient remained continent of urine throughout the management period.

Clinical environment and socioeconomic factors

The case was managed at KATH, a tertiary referral and teaching hospital in Kumasi, Ghana, serving a large population across several regions. The facility provides advanced surgical care but faces resource limitations, including the lack of a stoma specialist, shortages of specialised wound-care products, stoma appliances and NPWT.

The patient did not rely on public health insurance, as she was financially stable. Family support was strong, providing essential assistance with care coordination, financial costs, and emotional reassurance throughout her hospitalisation and recovery.

These environmental and socioeconomic factors significantly influenced wound management strategies, encouraging the adoption of improvised yet effective local techniques consistent with fistula management principles adapted for low-resource contexts.

Assessment of ileostomy and infected wound

Stoma assessment

The patient presented with a retracted end ileostomy located at the right iliac fossa (See Figure 1). The stoma was active, producing continuous output of semi-fluid chyme. It was totally detached from the peristomal skin, with visible mucocutaneous separation extending circumferentially.
The peristomal skin showed signs of infection, including erythema, maceration and localised tenderness. Frequent faecal leakage contributed to further skin breakdown and hindered pouch adherence, complicating stoma management. The high-output from the stoma increased the risk of dehydration and electrolyte imbalance, necessitating close monitoring using a fluid balance chart to record fluid intake and output.

 

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Figure 1. Retracted ileostomy stoma

 

Wound assessment

The patient’s abdominal wound was extensive, involving the lower abdominal and pelvic regions and extending superiorly toward the epigastric area (See Figure 1).

Clinical characteristics were:

  • Location: Lower abdomen extending toward the epigastrium.
  • Size and depth: The wound measured approximately 22cm in length, 15cm in width, and 4cm in depth, with irregular margins and exposure of subcutaneous tissue and underlying muscle layers.
  • Wound bed: Comprised of mixed tissue, with areas of bright red granulation, yellow-green slough, and patches of black necrotic tissue, indicating ongoing infection and delayed healing.
  • Wound edges: Rolled and irregular, with zones of undermining, particularly along the lateral margins.
  • Exudate: Heavy, thick, yellowish drainage with a foul odour, suggestive of bacterial colonisation and necrotic tissue breakdown.
  • Peri-wound skin: The surrounding skin appeared hyperpigmented but largely intact, with localised maceration near the wound margins caused by persistent exposure to moisture and faecal fluid.
  • Microbiology: A wound swab culture was obtained, which yielded mixed growth of coliform organisms, confirming secondary bacterial infection.

These findings indicated an infected, non-healing abdominal wound complicated by continuous contamination from stomal output and poor local wound conditions, which made effective containment of faecal fluid and wound-bed preparation particularly challenging.

Clinical impression

The combination of an active high-output ileostomy and mucocutaneous separation at the stoma site resulted in poor adhesion of the ostomy appliance, leading to recurrent leakages and secondary wound infection. The abdominal wound was deep and extensive, with exposure of subcutaneous tissue, rectus sheath, and portions of the rectus abdominis muscle, indicating significant soft-tissue loss and compromised healing potential.

The overall presentation represented a complex postoperative abdominal wound complicated by faecal contamination, peristomal maceration and ongoing infection. Effective management required a multidisciplinary approach, innovative strategies to control and contain ileostomy output, and continuous reassessment of the wound to facilitate deposition of granulation tissue and spontaneous healing within a resource-limited clinical setting.

Clinical management and outcomes

Initial management and assessment

Upon presentation, the patient’s abdominal wound was heavily contaminated with faecal fluid. The patient was managed using a multidisciplinary approach. The multidisciplinary team included surgeons, stoma specialist and nutritionist who met to discuss and evaluate possible clinical interventions.

The initial priorities and goals of care were to:

  1. Reduce gut motility and high faecal output with antimotility therapy.
  2. Suppress wound infection with systemic broad-spectrum antibiotics.
  3. Restore electrolyte imbalance with oral rehydration and provision of nutritional support with high-protein, high-calorie diet and stool bulking foods (despite their questionable nutritional value).
  4. Contain faecal output to minimise wound contamination.

Although the patient did not have a classic enterocutaneous fistula, but rather a complex wound with a high output ileostomy complicated by mucocutaneous separation the guiding principles of fistula management (SNAP), as advised by a consulting colorectal nurse specialist and stomaltherapist (Dee Waugh) were adopted. The core goals to be achieved were:

a. Effective control and containment of the faecal output

b. Wound-bed protection

c. Promotion of spontaneous healing under resource-limited conditions.

The multidisciplinary team, which included surgeons, stoma and wound therapists and a nutritionist met to evaluate possible interventions.

Debridement decision-making

Surgical sharp debridement was considered by the surgical team as part of wound-bed preparation. However, after team deliberation, surgical sharp debridement was not performed due to several clinical and contextual reasons:

  1. The wound bed showed areas of early granulation tissue interspersed with slough, indicating partial self-debridement.
  2. There was high risk of further bowel exposure or injury, given the proximity of the wound to the ileostomy.
  3. The patient’s hemodynamic status and nutritional condition were not optimal at the time, increasing procedural risk and post operative recovery.
  4. Theatre availability was limited and lack of access to NPWT also constrained surgical options.

Instead, the surgical team adopted a conservative mechanical wound debridement approach carried out by the stomal specialist, involving gentle mechanical cleansing with sterile normal saline using syringe and needle. Autolytic debridement was used through application of moisture-retentive dressings (saline-moistened gauze) to promote natural tissue breakdown or autolysis and slough removal. This conservative strategy aimed to protect fragile granulation tissue while reducing infection risk.

Consultation with colorectal nurse specialist and stomal therapist

A turning point (or game changer) occurred when consultation occurred with the colorectal nurse specialist and stomaltherapist. Photographs and wound progress notes were shared via secure professional communication channels.

The subsequent advice provided critical direction in three main ways:

  1. Reframing the approach to wound management: the treating team were advised to manage the case as a functional fistula, focusing first on faecal diversion and containment rather than attempting premature wound closure.
  2. Encouraging improvisation: Given the limited resources, it was recommended to create a localised isolation system around the stoma using available materials to contain faecal output, thereby mimicking the function of a fistula pouch.
  3. Enhancing multidisciplinary coordination: The importance of synchronising roles between surgical, nursing and nutritional teams and maintaining patient and family engagement in care support and decision-making was emphasised to the treating team.

This expert guidance fundamentally shifted the management strategy from conventional wound care toward a fistula-based containment model, which enabled significant wound improvement.

Outcome

Following implementation of these revised strategies:

  • Faecal leakage was effectively minimised using improvised containment techniques.
  • The wound was progressively debrided through autolysis, with a clean granulation bed forming within 10 days.
  • Gradual epithelialisation and spontaneous wound closure occurred over the following weeks without the need for surgical revision.
  • The patient regained mobility, resumed oral nutrition and achieved stable fluid and electrolyte balance.

The combined effect of expert consultation, multidisciplinary input, and family participation led to a positive clinical outcome despite the constraints of a low-resource environment.

Autolytic and mechanical wound debridement

The patient’s complex wound was managed using a combination of autolytic and mechanical debridement techniques to promote wound-bed preparation and granulation. The wound bed was irrigated with normal saline, while the periwound skin was gently cleansed with Savlon solution (containing cetrimide and chlorhexidine), which provided broad-spectrum antimicrobial activity to reduce surface bacterial load. Although Savlon is less commonly used in some settings due to the availability of more advanced antimicrobial cleansers, it remained a practical option in this resource-limited environment for controlling bioburden and preventing secondary infection.

A hydrocolloid dressing was applied in a picture-frame configuration around the wound margins to protect the peri-wound skin from maceration and to enhance the adhesion of the secondary dressing. The wound bed itself was overlaid with saline-moistened gauze, maintaining a moist environment conducive to autolytic debridement. The dressing was then secured with Tegaderm film, which was anchored onto the hydrocolloid frame rather than directly onto the skin to prevent further irritation and trauma to fragile peri-wound tissue. Dressing changes were performed once daily, or more frequently if leakage or saturation occurred, to maintain cleanliness, control exudate, and monitor healing progression.

Stoma and peristomal skin management

The detached end ileostomy was managed using ostomy paste, which was applied circumferentially around the stoma base to create a smooth, even surface and to enhance the seal of the appliance. This modification allowed for partial attachment of a Hollister one-piece ileostomy pouch (70mm), which was connected to a drainage bag to manage the high faecal output. Given the limited intact peristomal skin and persistent leakage, the pouch was changed daily to prevent maceration and contamination of the adjacent wound bed. This method provided temporary containment of faecal output, reduced local irritation, and facilitated progressive granulation and wound contraction (Figure 2).

 

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Figure 2. Stoma pouching, mechanical and autolytic dressing

 

Follow-up: Four days after debridement

Four days following the initiation of autolytic and mechanical debridement, the wound demonstrated significant clinical improvement. The wound bed was markedly cleaner, with extensive amounts of slough and necrotic tissue effectively removed. Wound edges appeared more regular, well-perfused, and viable, indicating progression toward granulation. Early signs of healthy tissue formation were evident across the wound surface, reflecting a positive response to the combined debridement and dressing strategy (Figure 3).

 

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Figure 3. Status of wound four days after debridement

 

Follow-up: Ten days after initial management

Ten days following the initiation of wound management regimen, the wound bed exhibited predominantly red and pink granulation tissue, with small areas of fibrinous material remaining. This indicated ongoing healing and a significant reduction in necrotic tissue compared to initial presentation (Figure 4).

A multidisciplinary discussion with the general and plastic surgical teams explored the option of wound flap closure (a surgical technique involving the transfer of tissue from an adjacent site to cover the defect, aimed at accelerating wound healing). However, the stoma team opted against this approach. This decision was based on several considerations:

The patient had already undergone three abdominal surgeries within a short period, increasing the risk of further complications.

The potential for wound breakdown remained high, particularly if the patient developed secondary infections (for example respiratory infection) leading to increased intra-abdominal pressure from coughing or straining.

Conservative, wound-centered management remained feasible and safer under the prevailing clinical and resource conditions.

 

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Figure 4. The status of the wound 10 days after initial management

 

Management of ileostomy and wound drainage or wound exudate: challenging phase

During this phase, the team faced a significant challenge in controlling the faecal fluid from the high-output ileostomy to prevent contamination of the healthy wound bed. The location of the detached stoma made conventional pouching difficult, increasing the risk of faecal -induced maceration and delayed healing.

1. To address this, the principles of fistula management were applied. A large Eakin fistula pouch was positioned over the peri-wound area to protect the surrounding skin, without attempting to isolate the stoma itself. Intermittent suction was applied using a mobile suction machine connected via an 18 Fr suction catheter. Continuous suction was avoided due to the device’s positive-pressure limitation, and the patient’s relative was trained to operate the machine intermittently (every 30minutes) and manipulate the catheter carefully, minimising trauma to the granulating tissue (Figure 5).

 

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Figure 5. Management of the ileostomy and wound drainage

 

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Figure 6. The status of the wound following one month

 

2. The high stoma output (approximately 2.5L daily) presented nutritional challenges. Early in this phase, there were differences in opinion between the stoma and nutritional teams. The stoma team recommended bulky, low-motility foods to reduce faecal volume, while the nutrition team prioritised nutritionally dense diets without consideration of their impact on stoma output. To reconcile these approaches, the team collaborated with the pharmacy department to initiate intravenous parenteral nutrition, prescribe antimotility medications (cap loperamide) and oral bulky food, such as banku, rice, yam and similar foods thus balancing nutritional needs with faecal output.

Throughout this phase, careful wound and stoma management successfully prevented overt infection, protected granulation tissue and maintained patient stability. The integration of fistula management principles, multidisciplinary collaboration, and family participation was essential in overcoming this complex care challenge.

Progressive wound healing and discharge planning

After two months and six days of intensive care, the patient demonstrated substantial clinical improvement. The wound was closing spontaneously, the stoma was adhering securely to the skin, faecal fluid had formed into solid stool, and the periwound skin appeared healthy.

The team initially planned to transition to standard wound care without the fistula pouch. However, due to limited availability of advanced dressing materials, such as foam or calcium alginate dressings, the team implemented the following routine wound care protocol: cleaning the wound with sterile gauze soaked in normal saline and covering it with povidine-iodine saturated gauze. Dressing changes were initially performed as needed, based on saturation, but later transitioned to every alternate day as the patient gained the ability to empty the pouch independently.

The type of ostomy appliance used depended on availability, with some pouches generously donated by Dee Waugh, which greatly facilitated patient care. The entire care team carefully evaluated the patient’s readiness for discharge, considering her prolonged hospitalisation. Prior to discharge a home care plan was established to support ongoing wound and stoma management, ensuring continuity of care and minimising the risk of post-discharge complications. Before discharge, the patient and family received comprehensive education and training in stoma and wound care, demonstrating competence in all necessary skills. They also received advice on dietary modification, fluid and electrolyte balance, and early signs of infection.

Post-discharge, regular home visits were conducted by the stoma care nursing team to monitor the stoma site, assess wound healing progress, and reinforce patient and caregiver competence in self-care. These visits also provided emotional support and practical guidance on managing the ostomy pouch and preventing skin complications. In addition, the patient attended scheduled weekly surgical outpatient reviews at Komfo Anokye Teaching Hospital (KATH) during the first month, followed by bi-weekly follow-ups as healing progressed. The combined hospital and home-based follow-up approach facilitated early detection of complications and ensured a smooth transition from hospital to home care (Figure 7).

 

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Figure 7. The status of the wound on discharge

 

Final outcome: Four months post-management

After four months of care, the patient’s wound had healed completely. The stoma was well-adhered to the peri-wound skin and functioning normally. A drainable ostomy appliance was now being used to manage the ileostomy. The patient and family demonstrated independent competence in stoma and wound care, with no signs of infection or skin complications. The successful outcome reflected the combined effect of multidisciplinary management, application of fistula principles, and family engagement, resulting in restored patient health and quality of life (Figures 8 and 9).

 

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Figure 8. Status of the healed wound and restored retracted stoma

 

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Figure 9. Pouched ileostomy stoma

 

Discussion

The management of complex abdominal wounds and high-output stomas in low-resource healthcare systems presents significant challenges due to limited access to advanced wound care materials, negative pressure systems, and specialised stoma appliances.10,17 In such contexts, clinicians often rely on clinical ingenuity, locally available resources, and multidisciplinary collaboration to achieve favorable outcomes.8,10,17 This case highlights how evidence-based principles of wound and fistula management were adapted successfully within a resource-limited setting to promote healing and restore anatomical function. Focusing on elements of SNAP21 (sepsis control, nutritional support, anatomy definition, and procedure planning) assisted the multidisciplinary team to review the patient holistically and collectively determine the initial clinical priorities, goals of care and management strategies to reduce sepsis, provide nutritional support appropriate to surgical recovery, adaptation of diet due to the Ileostomy and phases of wound healing and structural changes within the abdomen.

A critical decision in this case was the choice of autolytic and mechanical debridement over surgical sharp debridement. Although surgical debridement allows rapid removal of devitalised tissue, it was considered inappropriate given the patient’s recent multiple abdominal surgeries, high anesthetic risk, and fragile tissue condition. Evidence supports the use of autolytic and mechanical debridement in such high-risk or low-resource contexts, particularly when infection control and moisture balance can be maintained using hydrocolloid or hydrogel dressings.13 These methods promote gentle tissue removal and preserve viable structures, aligning with global wound care standards that emphasise moist wound healing environments to facilitate granulation and epithelialisation.23

The management of the high-output ileostomy and protection of peristomal skin were major challenges. The stoma produced approximately 2.5 litres of semi-liquid faecal fluid daily, leading to frequent leakage and skin maceration. Studies identify faecal leakage as a major contributor to peristomal contact dermatitis, infection and delayed wound healing.4,5,6 In this case, the principles of fistula management were applied, particularly containment of faecal fluid, wound isolation and protection of surrounding skin as discussed above. The use of an improvised fistula containment technique, similar in concept to negative pressure or suction-based wound management, minimised wound contamination and allowed progressive healing. This aligns with evidence supporting containment and NPWT-based approaches in the management of enterocutaneous fistulas and complex abdominal wounds.15,19

The success of this case was also underpinned by effective multidisciplinary collaboration among surgeons, stoma and wound nurses, psychologists and nutritionists. Such integrated teamwork has been shown to improve wound healing outcomes, reduce infection rates, and enhance stoma adaptation.8,9,21,24 Despite resource limitations, coordination between clinical teams and the involvement of the pharmacy unit for parenteral nutrition and antimotility therapy ensured optimal hydration, electrolyte balance and reduced stoma output.

Importantly, family engagement was central to the care plan. Caregiver participaton particularly in low-resource settings, is known to enhance treatment adherence, provide emotional support, and promote continuity of wound care.10 Training relatives to assist with pouching and effluent-control fostered a sustainable model for community-based care post-discharge.

Although flap closure was considered to accelerate wound closure, the decision to defer surgical reconstruction until full granulation occurred reflected sound clinical judgment. Evidence cautions that premature flap coverage of unstable or infected wounds increases the risk of recurrence and flap failure.15,16,22 Conservative management focusing on infection control, nutritional optimisation, and gradual granulation is consistent with best-practice recommendations for abdominal wound reconstruction.17,22 Ultimately, the wound achieved complete healing without the need for further surgery, an outcome demonstrating the efficacy of resource-appropriate, multidisciplinary wound management in a low-income setting.

Recommendations

1. Promote evidence-based, resource-conscious wound care:

In low-resource settings, autolytic and mechanical debridement using hydrocolloid or hydrogel dressings should be prioritised as safe, cost-effective alternatives to sharp debridement when infection control and moisture balance can be maintained.

2. Strengthen multidisciplinary collaboration:

Coordinated care among surgical, stoma, wound, nutritional and pharmacy teams is essential to improve wound outcomes, optimise nutritional status, and prevent infection.

3. Empower caregivers through training:

Active involvement and education of family members in stoma and wound care should be integrated into discharge planning to ensure continuity of care and reduce readmission risk.

4. Enhance access to advanced wound management technologies:

Health systems with low resources should explore cost-sharing, local innovation, or donor partnerships to expand access to Negative Pressure Wound Therapy (NPWT) and other evidence-based wound management tools.

Conclusion

This case underscores the importance of innovation, adaptability, and teamwork in the management of complex surgical wounds within resource-limited settings. The successful outcome achieved without access to advanced wound care technologies, demonstrates that evidence-based principles, such as maintaining a moist wound environment, infection control, and multidisciplinary collaboration can yield optimal healing outcomes. The incorporation of the SNAP principles of fistula management, as advised by the colorectal nurse specialist and stomaltherapist, along with patient and family engagement, proved transformative in ensuring both stoma and wound containment and psychosocial stability.

Ultimately, this experience highlights that sustainable wound and stoma care requires not only clinical expertise but also contextual creativity, effective interprofessional communication and empowerment of patients and caregivers. Strengthening such holistic, collaborative models can bridge the gap between ideal and feasible practice, improving outcomes for patients with complex postoperative wounds in low-resource environments.

Acknowledgement

The authors acknowledge the invaluable support and contributions of the following individuals and organisations:

General surgical team C, headed by Consultant Dr CK Dally, Komfo Anokye Teaching Hospital, Ghana.

Dee Waugh, colorectal nurse specialist and stomaltherapist, head of Forte Ability Institution, Stoma, Wound, and Incontinence, Cape Town, South Africa, for expert guidance in wound and stoma management.

South Africa Stoma Association for professional support and resources.

The stoma care team, led by Harriet Oppong Gyamfi (stoma specialist), Head of Stomal Care Unit, Komfo Anokye Teaching Hospital, Ghana.

The ward nursing staff, led by Banfowaah, head of surgical ward C3.

Donors and supporters, including Friends of Ostomy Worldwide (USA), IVES Team (UK), and generous individuals both locally and internationally, who provided essential stoma supplies and materials.

General surgery team, Komfo Anokye Teaching Hospital, for ongoing surgical and clinical support.

Conflict of interest

The authors declare no conflicts of interest.

Ethics statement

The authors affirm that this case study followed institutional ethical standards for clinical documentation and education at Komfo Anokye Teaching Hospital, Ghana. Written informed consent was obtained from the patient for the use of anonymised clinical information and images. All identifying details have been omitted to maintain confidentiality and privacy.

Funding

The authors received no funding for this study.


子宫肌瘤切除术后医源性肠损伤继发重度手术伤口裂开、继发性感染和暂时性回肠造口术:医疗资源匮乏环境下的挑战与管理

Jeffrey Tetteh Doku, Harriet Oppong Gyamfi

DOI: 10.33235/wcet.45.4.40-48

Author(s)

References

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摘要

本病例研究旨在重点阐述,针对子宫肌瘤切除术术中发生医源性肠损伤,进而引发重度手术伤口裂开、继发性感染并形成暂时性回肠造口的病例,所采用的简易且节约医疗资源的管理方法。本研究还展示了如何采用创新性伤口管理策略来控制和收纳粪便排泄物。具体措施包括使用止泻药物(洛哌丁胺)、摄入粪便増稠类食物,以及应用Eakin造口袋。尽管在医疗资源匮乏环境下,诊疗过程中面临造口定位不佳、黏膜皮肤分离等诸多挑战,但上述各项措施协同作用,顺利开展了伤口清创,并促进了伤口的自然愈合。

方法 本病例在复杂伤口的管理中,应用了瘘管管理、脓毒症控制、营养支持、解剖结构明确及手术规划(SNAP)原则。实施多学科团队协作诊疗模式,团队成员包含外科医师、造口护理专科人员、临床心理医师、病房护理人员和营养师。患者家属主动参与诊疗决策过程,并为患者提供了必要的经济与情感支持。额外采取的管理策略聚焦于粪便排泄物的收纳、伤口清创的推进、感染的预防,以及伤口自然愈合的促进。

结果 在临床医疗资源匮乏环境下,患者对该多学科诊疗方案应答良好。通过简易改良的瘘管管理技术,粪便排出物得到有效控制与收纳,最大程度减少了伤口污染,为逐步实施伤口清创创造了条件。临床观察可见伤口处健康肉芽组织逐步生长,进而实现伤口自发性收缩,最终伤口闭合愈合,无需进一步手术干预。整个康复期间,患者的营养状况与整体健康状态均得到显著改善。

引言与现有证据

手术伤口裂开合并继发性感染,仍是一类严重的术后并发症,特别是在接受急诊腹部手术并行造口术的患者中尤为常见。¹,²子宫肌瘤切除术是一种旨在切除子宫肌瘤,同时保留子宫的外科手术。该手术虽总体安全性良好,但因子宫与肠管及其他盆腔脏器解剖位置邻近,手术操作存在较高技术难度。3在子宫肌瘤切除术这类复杂或急诊手术中,可能发生肠管意外损伤,此类损伤称为医源性肠损伤。医源性肠损伤指手术操作中发生的非预期性穿孔或损伤,会増加腹腔污染、感染风险,进而诱发后续伤口破裂。4-6

发生此类肠损伤时,临床往往需行暂时性造口术(如回肠造口术),以转流粪便,保护远端肠管,并促进受损肠段或相关吻合口的愈合。6但在急诊场景下,受时间限制或术前规划不足的影响,造口定位效果可能不理想,进而引发造口装置渗漏、皮肤刺激及伤口进一步污染。5-6术后早期还可能出现黏膜皮肤分离,该病症指造口与周围皮肤发生部分或完全分离,7会暴露皮下组织,増加感染风险、延缓伤口愈合,并加重患者不适感。

电解质失衡是另一项潜在并发症,在高排量回肠造口患者中尤为显著,因为过量的液体与电解质丢失可引发脱水和代谢紊乱。8

在加纳这类医疗资源匮乏环境中,开展合并造口护理的复杂腹部伤口管理工作面临巨大挑战,原因在于先进伤口护理材料短缺、造口与伤口护理专业培训人员匮乏,且专科设备配备不足。9,10,11因此,有效的临床管理需采取多学科协作模式,整合外科、护理、营养及社会心理专业力量,同时推动家属主动参与患者照护。9-12严格遵循伤口床准备原则,包括清创、感染控制、湿度平衡和组织修复优化,是实现良好临床结局的核心前提。13,14

负压伤口治疗(NPWT)是一种通过向创面施加可控负压,促进肉芽组织生成、清除创面渗液的技术,该技术已被证实对合并或未合并造口的手术伤口裂开均具备良好的管理效果。15,16,17现有证据表明,NPWT可降低感染发生率、加速伤口闭合,并提升患者舒适度。18,19但在资源受限的医疗环境中,NPWT设备短缺、造口装置费用高昂,且专科伤口护理服务可及性不足,这些问题仍严重阻碍最优诊疗方案的实施。20上述挑战迫使临床医务人员立足资源现状,依据成熟的瘘管护理原则(SNAP)21和组织重建相关技术20-22,因地制宜改良并适配伤口管理策略与耗材。

本病例研究就此阐述了一种创新且节约医疗资源的管理方法,用于处理子宫肌瘤切除术术中发生医源性肠损伤,进而继发重度手术伤口裂开、继发性感染并接受暂时性回肠造口术的病例。同时本研究着重指出,在临床医疗资源匮乏环境下,造口定位欠佳与黏膜皮肤分离对伤口愈合和患者康复进程造成的影响。

个人病史与临床病史

患者为56岁女性,既往有子宫肌瘤、高血压病史,于2019年7月31日在加纳Ashanti地区Ejisu政府医院接受择期子宫肌瘤切除术。手术在全身麻醉下开展,腹部手术伤口予以一期分层缝合:筋膜和皮下组织采用可吸收缝线缝合,皮肤采用间断不可吸收缝线缝合。

患者术后即刻恢复过程初期无明显异常,然而在术后第1天(2019年8月1日),医护人员发现伤口敷料变为绿色,随即安排患者返回手术室行伤口探查与清创修整术。术后患者相继出现腹胀、伤口脓性渗出,且发生部分手术伤口裂开。两天内伤口裂开范围进一步扩大,深部肠管暴露。术中确诊患者存在医源性肠损伤并合并粪便污染,遂行转流性回肠造口术。

在再次开腹术后第2天(2019年8月3日),患者被转诊并转入Kumasi三级转诊中心Å\Å\Komfo Anokye教学医院(KATH),接受专科化的外科、伤口和造口诊疗管理。

合并症

患者既往病史明确,患有高血压,长期服用拉贝洛尔控制血压,另确诊子宫肌瘤。无糖尿病、肾功能损害等其他合并症。

用药情况

患者长期用药为拉贝洛尔,用于血压控制。针对头痛、发热等轻微症状,偶自行服用非处方止痛、退热药物对症处理。

过敏史

患者自述无已知食物、药物过敏史。

社会情况

患者已婚,育有三名子女(两男一女),与家人同住自有住房。日常有固定工作,生活作息规律且状态活跃,每日清晨先完成家务劳作后再前往工作。患者拥有良好的家庭及社交关系,患病期间始终获得家人持续的情感支持与经济支持。
尽管患者社会经济状况稳定,但仍表现出明显的社会心理困扰,将自身术后并发症迁延不愈的原因归咎于超自然因素或巫术影响(该观念是加纳部分地区民众对疾病的文化解读方式)。上述认知不仅影响了患者的心理健康状态,也对其康复初期的应对方式产生了作用。

伤口、造口和失禁评估

病因

该伤口并发症由子宫肌瘤切除术术中发生的小肠医源性损伤所致。对受损肠段予以一期修补,未行肠段切除;但术后修补部位愈合不良,引发粪便渗漏并继发腹膜炎,临床遂行转流性回肠造口术,以控制脓毒症、避免手术伤口进一步污染。

造口类型

患者行末端回肠造口术,术后造口周围出现完全性黏膜皮肤分离,导致造口装置难以实现良好贴合。这一情况引发粪便持续性渗漏,造成伤口床污染,进一步増加了伤口管理的难度。

造口排泄物

患者造口排泄量偏高,24小时平均排泄量约2.5升,由此引发体液和电解质失衡;富含消化酶的半流质食糜渗漏,还导致造口周围皮肤发生浸渍损伤。

造口护理

造口位于患者右下腹,但其定位欠佳,具体表现为造口位置低于脐水平线、处于腹直肌外侧,且部分陷入腹部皮肤褶皱内。该不良定位导致造口装置无法实现牢固密封。因此,早期造口袋佩戴尝试均以失败告终,粪便频繁渗漏、造口周围皮肤浸渍的问题持续存在,不仅造成邻近伤口进一步污染,还延缓了伤口愈合进程。后续临床管理中,需创新性改良伤口护理技术,包括对粪便排泄进行简易收纳管控,并对伤口周边皮肤实施精细化防护。

尿失禁

在全程诊疗管理期间,患者排尿功能正常,可自主控尿。

临床诊疗环境与社会经济因素

本病例于加纳Kumasi三级转诊教学医院(KATH)开展诊疗,该院为多个地区的大量人群提供医疗服务。该院可开展高级外科诊疗,但存在医疗资源受限问题,具体包括造口专科医师缺位、专科伤口护理用品、造口装置和NPWT设备短缺。

患者经济状况稳定,未依托公共医疗保险就医。家属给予其强有力的支持,在患者住院及康复全程,为其提供诊疗协调协助、费用支持与情感慰藉。

上述临床环境与社会经济因素,对伤口管理策略的制定产生了显著影响,促使医护人员结合医疗资源匮乏环境下的瘘管护理原则,采用因地制宜、简便且有效的本土化技术开展诊疗。

回肠造口与感染性伤口评估

造口评估

患者右髂窝处可见回缩性末端回肠造口(见图1),造口功能活跃,持续排出半流质食糜。造口与周围皮肤完全分离,且可见黏膜皮肤分离呈环周状延伸。
造口周围皮肤存在感染迹象,可见红斑、浸渍,伴局部触痛。粪便频繁渗漏进一步加重皮肤破溃,且导致造口袋无法有效黏附,増加造口管理难度。造口高排量排泄増加了患者脱水与电解质失衡的风险,需采用液体平衡表密切监测,完整记录患者液体出入量。

 

doku fig 1.png

图1.回肠造口回缩

 

伤口评估

患者腹部伤口范围广泛,累及下腹部和盆腔区域,并向上延伸至上腹部(见图1)。

临床特征如下:

  • 部位:下腹部,向上延伸至上腹部。
  • 大小与深度:伤口长约22 cm,宽约15 cm,深约4 cm;伤口边缘形态不规则,皮下组织和深部肌层外露。
  • 伤口床:创面组织类型混杂,可见鲜红色肉芽组织区、黄绿色腐肉区和黒色坏死组织斑片,提示创面存在持续性感染,愈合延迟。
  • 伤口边缘:边缘卷曲、形态不规则,伴潜行形成,以伤口外侧缘尤为明显。
  • 渗出物:渗出量多,分泌物黏稠、呈淡黄色,伴恶臭,表明创面存在细菌定植和坏死组织分解。
  • 伤口周围皮肤:周围皮肤色素沉着,但基本保持完整;受创面渗液与粪液持续刺激,伤口边缘局部出现皮肤浸渍。
  • 微生物学:伤口拭子培养结果显示大肠菌群混合生长,证实创面继发性细菌性感染。

上述评估结果提示,患者腹部伤口为感染性难愈性伤口,同时合并造口排泄物持续污染、局部创面条件差等问题,致使粪液的有效控存与伤口床准备工作面临极大挑战。

临床诊断印象

患者回肠造口功能活跃且高排量,合并造口部位黏膜皮肤分离,导致造口装置黏附效果差,进而引发造口反复渗漏,继发伤口感染。患者腹部伤口深且范围广泛,皮下组织、腹直肌鞘及部分腹直肌外露,提示存在严重软组织缺损,创面愈合潜力受损。

综合临床表现,本例为术后复杂腹部伤口,合并粪液污染、造口周围皮肤浸渍及持续性感染。在医疗资源受限的临床条件下,需采取多学科协作模式,制定创新策略控制并收纳回肠造口排泄物,同时对伤口进行持续评估,以促进肉芽组织生长,推动创面自然愈合。

临床管理与结局

初始管理与评估

患者就诊时,腹部伤口受粪液严重污染。临床对其采取多学科协作诊疗模式。参与诊疗的多学科团队包含外科医师、造口专科人员和营养师,经团队会诊讨论,评估拟定可行的临床干预方案。

初期护理的首要原则与目标为:

  1. 予止泻治疗,降低肠道蠕动频率,减少粪便高排量排泄。
  2. 予全身性广谱抗生素,抑制伤口感染。
  3. 予口服补液纠正电解质失衡,同时提供高蛋白、高卡路里饮食和粪便増稠类食物营养支持(尽管此类食物的营养价值尚存争议)。
  4. 做好粪便排泄物的收纳,最大限度减少伤口污染。

患者虽未形成典型肠外瘘,仅为合并高排量回肠造口、伴黏膜皮肤分离的复杂伤口,但经结直肠专科护士与造口治疗师(Dee Waugh)会诊指导,临床仍采用瘘管管理核心原则(SNAP)开展诊疗,拟定需达成的核心目标如下:

a. 有效控制并收纳粪便排泄物

b. 做好伤口床保护

c. 在资源受限条件下,促进创面自然愈合

多学科团队(外科医师、造口伤口治疗师、营养师)再次会诊,进一步评估各类干预方案的可行性。

清创决策

外科团队曾考虑外科锐性清创,作为伤口床准备的组成部分。但经团队综合研判,结合多项临床与实际诊疗条件,最终未实施锐性清创,原因如下:

  1. 伤口床可见早期肉芽组织与腐肉交错生长,提示部分创面已发生自体清创。
  2. 伤口与回肠造口位置邻近,实施锐性清创存在肠道再次外露或损伤的高风险。
  3. 患者当时的血流动力学状态与营养状况欠佳,若行手术清创,不仅会増加操作风险,且不利于术后恢复。
  4. 手术室资源有限,且院内缺乏NPWT设备,进一步限制了外科清创方案的实施。

基于此,外科团队选择采取保守性机械伤口清创方案,由造口专科人员执行操作:使用注射器与针头抽取无菌生理盐水,对创面进行轻柔的机械冲洗清洁。同时采用保湿敷料(生理盐水浸湿纱布)实施自溶性清创,促进组织自然溶解、腐肉脱落。该保守策略可保护脆弱的肉芽组织,同时降低创面感染风险。

结直肠专科护士与造口治疗师会诊

经结直肠专科护士与造口治疗师会诊后,诊疗迎来关键转折点。诊疗团队通过安全的专业沟通渠道,共享了患者创面照片与病情进展记录。

会诊后给出的指导意见,从三方面为诊疗工作指明了核心方向:

  1. 重塑伤口管理思路:建议诊疗团队将该病例按功能性肠瘘开展管理,优先实施粪便转流与收纳,而非尝试过早闭合伤口。
  2. 建议因地制宜开展改良操作:鉴于医疗资源有限,建议利用现有材料在造口周围创建局部隔离装置,实现粪便排泄物的收纳,模拟造口袋的功能。
  3. 强化多学科协作配合:向诊疗团队强调,需协调外科、护理、营养团队的工作职责,同时让患者及家属持续参与护理支持与诊疗决策。

该专业指导使诊疗策略从传统伤口护理模式,彻底转为基于肠瘘管理的排泄物收纳模式,患者创面也因此获得了显著改善。

结局

上述优化策略实施后,诊疗取得如下效果:

  • 采用改良收纳技术,粪便渗漏情况得到有效控制,渗漏量大幅减少。
  • 创面通过自溶性清创实现逐步脱痂,10日内即形成洁净的肉芽组织床。
  • 后续数周内,创面逐步上皮化并自然闭合,无需再次手术修整。
  • 患者恢复自主活动能力,恢复经口进食,水电解质水平趋于稳定。

尽管医疗资源有限,但在专业会诊指导、多学科协作诊疗与家属全程参与的共同作用下,患者最终临床结局良好。

自溶性与机械性伤口清创

针对患者的复杂伤口,临床联合采用自溶性清创与机械性清创技术,推进伤口床准备,促进肉芽组织生长。使用生理盐水冲洗伤口床,同时采用Savlon溶液(含西曲溴铵与氯己定)轻柔清洁伤口周边皮肤,借助其广谱抗菌作用降低皮肤表面细菌负荷。尽管在部分医疗环境中,因更先进抗菌清洗剂的普及,Savlon溶液的应用已逐渐减少,但在该低资源环境下,其仍是控制创面细菌负荷、预防继发性感染的实用选择。

在伤口边缘采用相框式贴敷水胶体敷料,保护伤口周边皮肤免受浸渍损伤,同时増强二级敷料的黏附效果。创面表面覆盖生理盐水浸湿的纱布,维持创面湿润环境,为自溶性清创创造条件。随后以Tegaderm膜固定上述敷料,该膜锚定于水胶体敷料边缘,而非直接贴附于皮肤,避免对脆弱的伤口周边组织造成进一步刺激与损伤。敷料每日更换一次,若出现渗漏或渗液浸透敷料,则及时更换,以此保持创面清洁、控制渗液,并实时监测创面愈合进展。

造口与造口周围皮肤管理

针对分离的末端回肠造口,临床于造口基部环形涂抹造口防漏膏,打造平整光滑的创面基底,提升造口装置的密封效果。经该处理后,可贴合使用一件式Hollister回肠造口袋(70 mm),并外接引流袋以应对高排量粪便排泄。因造口周围完整皮肤面积有限,且渗漏问题持续存在,造口袋需每日更换,避免造口周围皮肤发生浸渍、邻近伤口床受污染。该方法实现了粪便排泄物的临时收纳,减轻了局部刺激,同时为创面肉芽组织生长与伤口收缩创造了条件(图2)。

 

doku fig 2.png

图2.造口袋佩戴、机械性与自溶性清创敷料应用

 

随访:清创后四天

自启动自溶性与机械性清创治疗四天后,患者创面呈现显著的临床改善:伤口床清洁度大幅提升,大量腐肉及坏死组织被有效清除;伤口边缘形态更规整,血供良好、组织活性佳,提示创面正逐步向肉芽组织生长期过渡;创面全域可见健康组织生成的早期征象,表明联合清创与敷料护理方案收效良好(图3)。

 

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图3.清创后四天的伤口状态

 

随访:初始管理后十天

伤口管理方案实施十天后,伤口床以鲜红色、粉红色肉芽组织为主,仅残留少量纤维蛋白样物质,相较于初始状态,坏死组织占比显著降低,创面愈合进程持续推进(图4)。

 

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图4.初始管理后十天的伤口状态

 

诊疗团队联合普通外科与整形外科医师开展多学科会诊,探讨行皮瓣移植闭合伤口的可行性Å\Å\该外科技术通过转移邻近部位组织覆盖创面缺损,以期加速愈合。但造口专科团队最终否决了该方案,考量因素如下:

  1. 患者短期内已接受三次腹部手术,再次手术将大幅増加并发症发生风险。
  2. 伤口愈合不良的潜在风险仍较高,若患者继发感染(如呼吸器官感染),咳嗽、用力等动作会导致腹腔内压力増加,极易诱发伤口裂开。
  3. 在现有临床条件与医疗资源下,采取以创面为核心的保守治疗方案,兼具可行性与更高的安全性。

回肠造口与伤口引流、渗液管理:诊疗攻坚阶段

本阶段,诊疗团队面临的核心挑战为:管控高排量回肠造口的粪液排泄,避免健康的伤口床受到污染。造口分离的解剖位置导致常规造口袋佩戴难度大,粪液引发皮肤浸渍、延缓创面愈合的风险持续升高。

  1. 为解决该问题,团队参照瘘管管理原则开展干预:在伤口周边区域贴敷大号Eakin造口袋,重点保护周围皮肤,暂不尝试对造口本身进行隔离处理;通过18 Fr负压吸引管连接移动式负压吸引装置,为创面实施间断负压吸引。因设备存在正压限制,未采用持续负压吸引模式,同时培训患者家属掌握装置操作方法,每30分钟进行一次间断吸引,并规范操作吸引管,最大限度减少对肉芽组织的损伤(图5)。
  2. 造口高排量排泄(每日约2.5 L)也带来了营养管理难题。本阶段初期,造口专科团队与营养团队存在诊疗意见分歧:造口团队建议给予粪便増稠、低肠道蠕动类食物,减少粪便排泄量;营养团队则优先推荐高营养密度饮食,未考量其对造口排泄量的影响。为兼顾双方诊疗需求,团队联合药剂科制定综合方案:为患者启动静脉肠外营养支持,开具止泻药物(洛哌丁胺胶嚢),同时指导患者摄入班库粥、米饭、山药等经口増稠类食物,实现营养需求与粪便排泄管控的双向平衡。

 

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5.回肠造口与伤口引流的管理

 

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6.护理1个月后的伤口状态

 

本阶段内,通过精细化的伤口与造口管理,有效规避了创面显性感染的发生,保护了肉芽组织生长,患者病情始终保持稳定。瘘管管理原则的应用、多学科协作配合与家属全程参与,成为攻克本次复杂护理难题的核心关键。

伤口逐步愈合与出院规划

经两个月零六天的强化治疗,患者病情取得实质性好转:伤口呈自然闭合趋势,造口与周围皮肤贴合良好,粪液性状转为成形粪便,伤口周边皮肤恢复健康状态。

诊疗团队最初计划停用造口袋,转为标准伤口护理模式,但因院内泡沫敷料、藻酸钙敷料等高级敷料短缺,最终制定如下常规伤口护理方案:以无菌生理盐水浸湿纱布清洁伤口,随后覆盖聚维酮碘饱和纱布。敷料更换频次初期依据渗液浸透情况按需执行,待患者可独立完成造口袋排空操作后,调整为隔日更换一次。

造口装置的选用以院内物资供应情况为准,造口治疗师Dee Waugh无偿捐赠了部分造口袋,为患者诊疗提供了极大支持。结合患者长期住院的实际情况,全体医护团队综合评估其出院指征,于出院前制定完善的居家护理方案,保障伤口与造口后续管理的持续性,降低出院后并发症发生风险。出院前,医护人员为患者及家属开展造口与伤口护理全流程宣教及实操培训,确保其熟练掌握各项必备技能;同时指导患者调整饮食方案、维持水电解质平衡,并告知感染早期迹象。

出院后,造口护理专科团队定期上门随访,监测造口情况、评估伤口愈合进展,强化患者与照护者的自我护理能力,同时为其提供情感支持,指导造口袋规范使用、皮肤并发症预防等实操要点。此外,患者出院后首个月需前往Komfo Anokye教学医院(KATH)外科门诊完成每周复诊,创面愈合后复诊频次调整为每两周一次。院内诊疗联合居家随访的模式,实现了并发症的早发现、早干预,保障患者顺利完成从院内治疗到居家护理的过渡(图7)。

 

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图7.出院时的伤口状态

 

最终结局:管理后四个月

经四个月的护理,患者伤口完全愈合。造口与周围皮肤贴合紧密,造口功能恢复正常,现可使用可排空式造口装置开展回肠造口管理。患者及家属可独立完成造口与伤口的全部护理操作,创面无感染、皮肤并发症等迹象。本次诊疗的良好结局,是多学科协作诊疗、瘘管管理原则应用与家属全程参与共同作用的结果,患者的健康状态与生活质量均得以恢复(图8和图9)。

 

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图8.伤口愈合和回缩造口修复后状态

 

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图9.佩戴造口袋的回肠造口

 

讨论

在医疗资源匮乏的卫生体系中,复杂腹部伤口与高排量造口的临床管理面临重重挑战,原因在于高级伤口护理材料、负压治疗设备及专用造口装置的可及性均十分有限。10,17在此类医疗背景下,临床工作者往往需依托临床应变能力、本地可获取的医疗资源和多学科协作,方能实现理想的治疗效果。8,10,17本病例证实,在资源受限的诊疗环境中,将循证的伤口与瘘管管理原则灵活应用,可有效促进创面愈合、恢复机体解剖功能。以SNAP21原则(脓毒症控制、营养支持、解剖结构明确、手术方案规划)为核心开展诊疗,助力多学科团队对患者实施整体评估,共同制定了初期临床诊疗重点、护理目标及管理策略,实现了脓毒症控制、适配外科术后恢复的营养支持供给,同时结合回肠造口特点、伤口愈合不同阶段及腹腔内组织结构变化,完成了患者的饮食调整。

本病例中一项关键性决策为:选用自溶性清创联合机械性清创方案,而非外科锐性清创。尽管外科锐性清创可快速清除失活组织,但结合患者近期接受多次腹部手术、麻醉风险高、局部组织状态脆弱的现状,认为不适宜进行外科锐性清创。已有循证证据证实,在这类高风险或资源匮乏的诊疗场景中,自溶性与机械性清创具备应用合理性,尤其在可通过水胶体或水凝胶敷料实现感染控制与创面湿度平衡时,优势更为显著。13上述清创方式可温和清除坏死组织、保留存活组织结构,与国际伤口护理标准的核心要求相符Å\Å\该标准强调通过维持创面湿性愈合环境,促进肉芽组织生长与上皮化进程。23

高排量回肠造口的管理与造口周围皮肤的防护,是本次诊疗的两大核心难题。患者造口每日排泄约2.5升半液态粪液,易引发造口反复渗漏和皮肤浸渍。已有研究证实,粪液渗漏是造成造口周围接触性皮炎、感染和伤口愈合延迟的主要诱因。4,5,6本病例中,团队应用瘘管管理原则开展护理,核心措施如前文所述,重点实现粪液收纳、伤口隔离及周围皮肤防护。本研究采用的改良式瘘液收纳技术,与负压吸引式伤口管理理念相通,有效减少了伤口污染,为创面逐步愈合创造了条件。该护理思路与现有循证证据一致,相关证据均支持在肠外瘘和复杂腹部伤口的管理中,采用排泄物收纳与NPWT的护理方案。15,19

本病例诊疗取得成功,同样离不开外科医师、造口伤口专科护士、心理医师与营养师的高效多学科协作。已有研究表明,这类一体化团队协作模式可提升伤口愈合效果、降低感染发生率,并促进患者适应造口生活。8,9,21,24尽管医疗资源受限,各临床团队仍实现了高效协作,药剂科也参与其中,为患者提供肠外营养与止泻治疗支持,保障患者水电解质平衡处于最佳状态,同时减少了造口排泄量。

值得重视的是,家属参与是本次护理方案的核心环节。已有研究证实,在医疗资源匮乏地区,照护者的参与可显著提升患者的治疗依从性、为患者提供心理支持,并保障出院后伤口护理的持续性。10通过培训患者家属掌握造口袋佩戴与排泄物管控技能,为患者出院后开展社区居家护理搭建了可持续的管理模式。

诊疗过程中,团队曾考虑采用皮瓣移植术加速伤口闭合,但最终决定待创面完全形成肉芽组织后,再开展外科修复手术,该决策体现了严谨的临床判断。循证证据警示,若对未稳定或合并感染的伤口过早实施皮瓣覆盖,会増加病情复发与皮瓣坏死的风险。15,16,22以感染控制、营养优化、肉芽组织逐步生长为核心的保守治疗方案,与腹部伤口修复的最佳临床实践指南要求一致。17,22最终,患者创面实现完全愈合,无需接受进一步外科手术。这一治疗结局证实,在低收入地区,结合本地资源制定的多学科伤口管理方案具备确切疗效。

建议

1. 推广循证且适配医疗资源的伤口护理方案:

在医疗资源匮乏地区,若可实现感染控制与创面湿度平衡,临床应优先采用水胶体或水凝胶敷料开展自溶性清创与机械性清创,该方案安全且性价比高,可作为外科锐性清创的替代手段。

2. 强化多学科协作诊疗:

外科、造口、伤口护理、营养及药剂团队开展协同诊疗至关重要,此举可改善伤口愈合结局、优化患者营养状况,并预防感染发生。

3. 开展照护者培训,提升照护能力:

应将家属造口与伤口护理相关培训、引导家属主动参与护理,纳入患者出院规划中,保障护理的持续性,降低再入院风险。

4. 提升先进伤口管理技术的可及性:

资源匮乏的卫生体系应探索成本分担、本土创新或捐赠合作等模式,扩大负压伤口治疗(NPWT)及其他循证伤口管理器械的临床应用范围。

结论

本病例证实,在资源受限的医疗环境中开展复杂手术伤口管理,创新诊疗思路、灵活适配资源与团队协作缺一不可。即便缺乏先进伤口护理技术支持,本病例仍取得良好结局,这表明遵循湿性创面愈合、感染控制、多学科协作等循证原则,即可实现理想的创面愈合结局。经结直肠专科护士与造口治疗师指导,诊疗团队融入瘘管管理的SNAP原则,并推动患者及家属全程参与诊疗,这一举措产生了关键性作用,不仅实现了造口与伤口排泄物的有效管控,也保障了患者的身心状态稳定。

综上,本次诊疗经验表明,开展可持续的伤口与造口护理工作,不仅需要扎实的临床专业能力,更要结合临床实际灵活施策、实现高效的跨专业沟通,并充分提升患者与照护者的自我护理能力。强化此类整体化、协作式的诊疗模式,可有效缩小理想诊疗方案与临床可行方案之间的差距,进而改善资源匮乏地区复杂术后伤口患者的治疗结局。

致谢

本文作者衷心感谢以下个人和机构给予的宝贵支持与贡献:

由顾问医生CK Dally博士领导的C组普外科团队,Komfo Anokye教学医院,加纳。

Dee Waugh,结直肠护士专家和造口治疗师,Forte Ability Institution的造口、伤口和失禁护理部门负责人,南非开普敦,为本病例的伤口与造口管理提供专业指导。

南非造口协会提供的专业支持和资源。

由Harriet Oppong Gyamfi(造口专家)领导的造口护理团队,造口护理科,Komfo Anokye教学医院,加纳。

由Banfowaah(C3外科病房负责人)领导的病房护理团队。

捐赠者和支持者,包括来自Friends of Ostomy Worldwide(美国)、IVES团队(英国),以及本地和国际上慷慨捐赠的个人,为本研究提供了必需的造口耗材与物资。

普通外科团队,Komfo Anokye教学医院,为本病例提供全程外科诊疗与临床支持。

利益冲突

作者声明无任何利益冲突。

伦理声明

本文作者确认,本病例研究严格遵循加纳Komfo Anokye教学医院关于临床资料记录与教学的机构伦理规范。已获得患者书面知情同意,允许使用其匿名化的临床资料与影像资料。所有可识别患者身份的信息均已隐匿处理,以保障患者隐私与保密权益。

资助

作者未因该项研究收到任何资助。


Author(s)

Jeffrey Tetteh Doku* RN BSc
Stomal Specialist
Komfo Anokye Teaching Hospital Dept of Surgery
Kumasi, Ghana
Email Jeffdok81@gmail.com

Harriet Oppong Gyamfi RN BSc
Stomal Specialist
Komfo Anokye Teaching Hospital Dept of Surgery
Kumasi, Ghana

* Corresponding author

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