Volume 41 Number 2

Synthesising evidence

Jenny Prentice

For referencing Prentice J. Synthesising evidence. WCET® Journal 2021;41(2):6

DOI https://doi.org/10.33235/wcet.41.2.6





Our aspiration to achieve Medline Indexing was discussed in 20181. Recently it came to our attention that Medline’s parameters for assessing journals applicability for gaining Medline Index status had changed. This has implications for publishers, editors, and authors. Consequently, within this and future editorials the focus will be on expectations of authors in developing articles for publication within the WCET® Journal.  Here the CARE Checklist for writing case reports is provided2,3. Peer reviewers will use this checklist to determine authors adherence to this checklist when preparing a case report. This will ensure greater consistency in writing case reports/studies and confidentiality of patient information. Simultaneously, the WCET® Author Guidelines will be updated to reflect inclusion of the CARE Checklist criteria.

The inclusion of evidence summaries from low- and middle-income countries as a regular feature in the WCET® Journal is a welcome collaboration with the Wound Healing and Management (WHAM) unit, Curtin University, Western Australia. This first summary discusses evidence to support the use of topical coconut products in wound management and the treatment of skin conditions in humans. The WHAM are thanked for their generosity in sharing this information with WCET® members.

With kind regards



Jenny Prentice

DOI: https://doi.org/10.33235/wcet.41.2.6









Jenny Prentice


  1. Prentice J. Medline indexing: Aspiring to reach for the stars. WCET Journal 2018; 38 (4): 10-11.
  2. Gagnier JJ, Kienle G, Altman DG, Moher D, Sox H, Riley D; the CARE Group. The CARE Guidelines: Consensus-based Clinical Case Reporting Guideline Development.
  3. https://www.equator-network.org/reporting-guidelines/srqr/




2013 CARE Checklist

Title – The diagnosis or intervention of primary focus followed by the words “case report”.

Key Words – 2 to 5 key words that identify diagnoses or interventions in this case report (including “case report”).

Abstract – (structured or unstructured)

  • Introduction – What is unique about this case and what does it add to the scientific literature?
  • The patient’s main concerns and important clinical findings.
  • The primary diagnoses, interventions, and outcomes.
  • Conclusion – What are one or more “take-away” lessons from this case report?

Introduction – Briefly summarizes why this case is unique and may include medical literature references.

Patient Information

  • De-identified patient specific information.
  • Primary concerns and symptoms of the patient.
  • Medical, family, and psychosocial history including relevant genetic information.
  • Relevant past interventions and their outcomes.

Clinical Findings – Describe significant physical examination (PE) and important clinical findings.

Timeline – Historical and current information from this episode of care organized as a timeline (figure or table).

Diagnostic Assessment

  • Diagnostic methods (PE, laboratory testing, imaging, surveys).
  • Diagnostic challenges.
  • Diagnosis (including other diagnoses considered).
  • Prognostic characteristics when applicable.

Therapeutic Intervention

  • Types of therapeutic intervention (pharmacologic, surgical, preventive).
  • Administration of therapeutic intervention (dosage, strength, duration).
  • Changes in therapeutic interventions with explanations.

Follow-up and Outcomes

  • Clinician- and patient-assessed outcomes if available.
  • Important follow-up diagnostic and other test results.
  • Intervention adherence and tolerability. (How was this assessed?)
  • Adverse and unanticipated events.


  • Strengths and limitations in your approach to this case.
  • Discussion of the relevant medical literature.
  • The rationale for your conclusions.
  • The primary “take-away” lessons from this case report (without references) in a one paragraph conclusion.

Patient Perspective – The patient should share their perspective  on the treatment(s) they received.

Informed Consent – The patient should give informed consent. (Provide if requested.)

The CARE checklist (and writing outline) have been translated into multiple languages.





标题 - 主要关注的诊断或干预措施,随后是“病例报告”等词。

关键字 - 2至5个关键词,以明确这篇病例报告中的诊断或干预措施(包括“病例报告”)。

摘要 -(结构化或非结构化)

引言 - 这个病例的独特之处,它对科学文献有何贡献?

• 患者的主要问题和重要的临床研究结果。

• 主要诊断、干预措施和结果。

结论 - 这篇病例报告中有哪些“值得借鉴”的经验?

引言 - 简要概述这个病例的独特之处,可包括医学文献的参考文献。


• 去识别化的患者身份的具体信息。

• 患者的主要问题和症状。

• 医疗、家庭和心理社会史,包括相关的遗传信息。

• 过去的相关干预措施及其结果。

临床研究结果 - 描述关键的体检(PE)情况和重要的临床研究结果。

时间线 - 以时间线(图或表)的形式组织该护理过程中的历史信息和当前信息。


• 诊断方法(PE、实验室测试、成像、调查)。

• 诊断方面的挑战。

• 诊断(包括考虑的其他诊断)。

• 预后特征(适用时)。


• 治疗性干预措施的类型(药物、手术、预防)。

• 治疗性干预措施的管理(剂量、强度、持续时

• 治疗性干预措施的变化,并说明理由。


• 临床医生和患者评估的结果(如有)。

• 重要的随访诊断和其他测试结果。

• 干预措施的依从性和耐受性。(这是如何评估

• 不良事件和非预期事件。


• 您处理此病例所用方法的优势和局限性。

• 对相关医学文献的讨论。

• 您得出结论的依据。

• 在结论段落中说明这篇病例报告(不含参考文献)的主 要“借鉴”经验。

患者看法 - 患者应分享其对所接受治疗的看法。

知情同意书 - 患者应给予知情同意书。(根据要求提供。)